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Bidirectional Mendelian randomization to explore the causal relationships between schizophrenia and narcolepsy.

Schizophrenia research - 1 Dec 2024

Geng Chaofan, Chen Chen

Abstract excerpt

INTRODUCTION: This study employs the Mendelian Randomization (MR) approach to explore the potential causal relationship between schizophrenia and the risk of developing narcolepsy. METHODS: Genome-Wide Association Studies (GWAS) data from European populations were used to identify independent genetic variants associated with schizophrenia and narcolepsy, which were then used as instrumental variables in the...

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PMID: 39461090
DOI: 10.1016/j.schres.2024.10.007

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