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Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response

19 Sept 2023

Abstract excerpt

BACKGROUND AND AIMS: Hepatoblastoma (HB) is the predominant form of pediatric liver cancer, though it remains exceptionally rare. While treatment outcomes for children with HB have improved, patients with advanced tumors face limited therapeutic choices. Additionally, survivors often suffer from long-term adverse effects due to treatment, including ototoxicity, cardiotoxicity, delayed growth, and secondary...

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PMID: 37729391
DOI: 10.1097/hep.0000000000000601

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