Article
ABO-adjusted cPRA metric for kidney allocation in an Asian-predominant population.
HLA - 1 Jan 2024
Lau Kei Man, Chu Patrick W K, Tang Lydia W M, Chen Bryan P Y, Yeung Nicholas K M, Ip Patrick, Lee Pamela, Yap Desmond Y H, Kwok Janette S Y
Abstract excerpt
Recent studies showed that ABO-adjusted calculated panel reactive antibody (ABO-cPRA) may better reflect the histocompatibility level in a multi-ethnic population, but such data in Asians is not available. We developed an ABO-adjusted cPRA metric on a cohort of waitlist kidney transplant patients (n = 647, 99% Chinese) in Hong Kong, based on HLA alleles and ABO frequencies of local donors. The concordance between...
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