Article
Simulation of non-inherited maternal antigens acceptable HLA mismatches to increase the chance of matched cord blood units: Hong Kong's experience.
Human immunology - 1 Jul 2018
Kwok Janette, Guo Mengbiao, Yang Wanling, Ip Patrick, Lee C K, Lu Liwei, Chan Godfrey C F, Middleton Derek, van der Zanden Henk G M
Abstract excerpt
In Cord blood transplantation (CBT), the non-inherited maternal antigen (NIMA) virtual six HLA matched CB is found to have similar outcomes to six HLA inherited matched CB. Such virtual HLA matched CB units can be generated by substituting the inherited alleles with one to three NIMAs. In Hong Kong Cord Blood Bank, CB units have no NIMA defined. 100 CB samples were collected with NIMA defined. Retrospective...
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