Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Prognostic and Functional Impact of Sprouty 2 Expression in Non-small Cell Lung Cancer.

American journal of clinical oncology - 1 Dec 2023

Acikgoz Yusuf, Yildirim Fatma Unal, Esen Selin Akturk, Ucar Gokhan, Ergun Yakup, Bal Oznur, Dogan Mutlu, Uncu Dogan

Abstract excerpt

OBJECTIVE: We represent Sprouty 2 (Spry2) expression analysis and its association with key driver mutations and clinical features of patients with non-small cell lung cancer as the largest ex vivo data. METHODS: The strength of Spry2 expression was evaluated using the immunoreactivity score (IRS), which was calculated using the following formula: IRS=(staining intensity score) SI×(percentage of positively stained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Prognosis

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 37700432
DOI: 10.1097/COC.0000000000001044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Prognostic and Functional Impact of Sprouty 2 Expression in Non-small Cell Lung Cancer.PMID 37700432Read ↗

Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms.Semantic proximity Read ↗

The Clinical Significance and Potential Molecular Mechanisms of Synaptojanin 2 in Lung AdenocarcinomaSemantic proximity Read ↗

Role of SPRY4 in health and diseaseSemantic proximity Read ↗

High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.Semantic proximity Read ↗

SPRR3 as a diagnostic and prognostic molecular marker for lung adenocarcinoma based on pan-cancer analysisSemantic proximity Read ↗

SYNGR2 plays a tumor-promoting role in lung adenocarcinoma through PI3K-AKT signaling pathwaySemantic proximity Read ↗

The Sprouty/Spred family as tumor suppressors: Coming of ageSemantic proximity Read ↗

Clinical potential of SKP2 as diagnostic marker and therapeutic target in small cell lung cancer.Semantic proximity Read ↗

RACK1 Promotes Non-small-cell Lung Cancer Tumorigenicity through Activating Sonic Hedgehog Signaling PathwaySemantic proximity Read ↗

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling.Semantic proximity Read ↗

Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.Semantic proximity Read ↗

SHP2 Inhibition Benefits Epidermal Growth Factor Receptor-mutated Non-Small Cell Lung Cancer Therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.