Article

The Clinical Significance and Potential Molecular Mechanisms of Synaptojanin 2 in Lung Adenocarcinoma

2020-06-16

Abstract excerpt

<title>Abstract</title> <p>Background Lung adenocarcinoma (LUAD) is the main pathological type of pulmonary malignant tumors. Synaptojanin 2 (SYNJ2), a member of the synaptojanin family, is considered as an attractive underlying therapeutic target in several types of cancer. The purpose of the current research was to comprehensively investigate the molecular function and underlying mechanism of SYNJ2 in LUAD wit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1e61a01-9a80-5fe4-9387-ea9225ebfea4
DOI: 10.21203/rs.3.rs-35107/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Clinical Significance and Potential Molecular Mechanisms of Synaptojanin 2 in Lung AdenocarcinomaDOI 10.21203/rs.3.rs-35107/v1Read

Identifying the Prognostic Risk Factors of Synaptojanin 2 and Its Underlying Perturbations Pathways in Hepatocellular CarcinomaSemantic proximity Read

SYNGR2 plays a tumor-promoting role in lung adenocarcinoma through PI3K-AKT signaling pathwaySemantic proximity Read

SYT2/11/13/15 Are Potential Prognostic Biomarkers and Correlate to Immune Infiltration in Lung AdenocarcinomaSemantic proximity Read

PLEK2 and SCN7A: novel biomarkers of non-small cell lung cancerSemantic proximity Read

PLEK2 and SCN7A: novel biomarkers of non-small cell lung cancerSemantic proximity Read

Synaptopodin-2: a potential tumor suppressorSemantic proximity Read

SYNGR2 Serves as a Prognostic Biomarker and Correlated with Immune Infiltrates in Esophageal Squamous Cell CarcinomaSemantic proximity Read

Aberrant expression of JAM2 inhibits invasion and migration in lung adenocarcinomaSemantic proximity Read

RYR2 mutation in non-small cell lung cancer prolongs survival via down-regulation of DKK1 and up-regulation of GS1-115G20.1: A weighted gene Co-expression network analysis and risk prognostic models.Semantic proximity Read

EXOSC5: A Novel Biomarker for Poor Prognosis in Lung AdenocarcinomaSemantic proximity Read

Integrated analysis unraveling the immunologic and clinical prognostic values of Synaptotagmin Like 4 in pan-cancerSemantic proximity Read

PLEK2 promotes lung adenocarcinoma progression via activating the PI3K/AKT signaling pathway through SPC25 Running title: PLEK2 promotes LUAD via SPC25/PI3K/AKT axisSemantic proximity Read