Article
Impact of Genetic Loci Identified in Genome-Wide Association Studies on Diabetic Retinopathy in Chinese Patients With Type 2 Diabetes.
Investigative ophthalmology & visual science - 1 Oct 2016
Cheung Chloe Y Y, Hui Elaine Y L, Lee Chi-Ho, Kwok Kelvin H M, Gangwani Rita A, Li Kenneth K W, Chan Jeffrey C W, Woo Yu-Cho, Chow Wing-Sun, Yuen Michele M A, Wong Rachel L C, Fong Carol H Y, Xu Aimin, Wong David S H, Sham Pak-Chung, Lam Karen S L
Abstract excerpt
PURPOSE: Diabetic retinopathy (DR) is a common microvascular complication of type 2 diabetes (T2DM). Genome-wide association studies (GWAS) had identified novel DR-susceptibility genetic variants in various populations. We examined the associations of these DR-associated single nucleotide polymorphisms (SNPs) with severe DR in a Chinese T2DM cohort. METHODS: Cross-sectional case-control studies on...
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