Article
Ectopic expression of HNF4α in Het1A cells induces an invasive phenotype.
Differentiation; research in biological diversity - 1 Jan 2000
Grimaldos Rodriguez Carmen, Rimmer Ella F, Colleypriest Benjamin, Tosh David, Slack Jonathan M W, Jungwirth Ute
Abstract excerpt
Barrett's oesophagus (BO) is a pathological condition in which the squamous epithelium of the distal oesophagus is replaced by an intestinal-like columnar epithelium originating from the gastric cardia. Several somatic mutations contribute to the intestinal-like metaplasia. Once these have occurred in a single cell, it will be unable to expand further unless the altered cell can colonise the surrounding squamous...
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