MBOAT7 rs641738 Variant Is Not Associated with an Increased Risk of Hepatocellular Carcinoma in a Latin American Cohort.

doi:10.1007/s10620-023-08104-y

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MBOAT7 rs641738 Variant Is Not Associated with an Increased Risk of Hepatocellular Carcinoma in a Latin American Cohort.

Digestive diseases and sciences - 1 Nov 2023

Goble Spencer, Akambase Joseph, Prieto Jhon, Balderramo Domingo, Ferrer Javier Diaz, Mattos Angelo Z, Arrese Marco, Carrera Enrique, Groothuismink Zwier M A, Oliveira Jeffrey, Boonstra Andre, Debes Jose D

Abstract excerpt

BACKGROUND: The rs641738 C > T single-nucleotide polymorphism of MBOAT7 has been associated with hepatocellular carcinoma (HCC) and nonalcoholic fatty liver disease (NAFLD). Latin Americans have high rates of HCC and NAFLD, but no assessment between MBOAT7 and HCC has been performed in this population. AIMS: We provide the first assessment of the impact of MBOAT7 on HCC risk in Latin Americans. METHODS: Patients...

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PMID: 37684433
DOI: 10.1007/s10620-023-08104-y
PMCID: PMC10570183

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