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Article

Th17 cells in cancer: help or hindrance?

8 Feb 2011

Abstract excerpt

The role of CD4+ T helper (Th) 17 cells in malignancy is currently under debate. However, upon closer scrutiny, it becomes apparent that this discussion includes not only evaluations of Th17 cells but also IL-17+ cells from other immune populations, the cytokine interleukin (IL)-17 itself (both endogenous and exogenous) and IL-23. Further complicating the matter are occasionally conflicting results of studies in...

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PMID: 21304053
DOI: 10.1093/carcin/bgr019

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