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Article

Mutational signatures and their association with survival and gene expression in urological carcinomas.

Neoplasia (New York, N.Y.) - 1 Oct 2023

Karihtala Peeter, Kilpivaara Outi, Porvari Katja

Abstract excerpt

Different sources of mutagenesis cause consistently identifiable patterns of mutations and mutational signatures that mirror the various carcinogenetic processes. We used publicly available data from the Cancer Genome Atlas to evaluate the associations between the activity of the mutational signatures and various survival endpoints in six types of urological cancers after adjusting for established prognostic...

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Identifiers

PMID: 37678146
DOI: 10.1016/j.neo.2023.100933
PMCID: PMC10495641

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