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An ex vivo model of Toxoplasma recrudescence reveals developmental plasticity of the bradyzoite stage

7 Sept 2023

Abstract excerpt

ABSTRACT The recrudescence of Toxoplasma cysts is the cause of clinical disease in the immunocompromised. Although Toxoplasma has been a useful parasite model for decades because it is relatively easy to genetically modify and culture, attempts to generate and study the recrudescence of tissue cysts have come up short with cell culture-adapted strains generating low numbers of tissue cysts in vivo . Taking...

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PMID: 37675999
DOI: 10.1128/mbio.01836-23

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