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Article

Key genes in the liver fibrosis process are mined based on single-cell transcriptomics

29 Jan 2022

Abstract excerpt

At present, there is no effective treatment for liver fibrosis, and treatment options are limited. Liver fibrosis remains a cancer with a high mortality rate. During liver injury, hepatic stellate cells transdifferentiate into myofibroblasts capable of proliferation, migration, and invasion. The transcriptomes of more than 60,000 human single cells were analyzed in 9 cirrhotic tissue samples and 11 normal liver...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35168183
DOI: 10.1016/j.bbrc.2022.01.094

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