Article

Human blood vessel organoids reveal a critical role for IGFBP7 in Diabetic Microangiopathy

2026-07-29

Abstract excerpt

Microangiopathy is a key contributor to diabetic vascular complications. There is currently no effective treatment, and patients are at high risk of major adverse cardiovascular events. We have recently demonstrated that human blood vessel organoids (BVOs) capture key aspects of the microvasculature. Here, employing patient derived BVOs we find that diabetic media treated BVOs display features of diabetic clinical...

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Literature Corpus work: 7f572afb-f02a-54b0-b3a5-c86e537f0ba4
DOI: 10.64898/2026.07.26.26358752

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