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Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma

22 Feb 2023

Abstract excerpt

BACKGROUND: Mitochondria represent a major source of reactive oxygen species (ROS) in cells, and the direct increase in ROS content is the primary cause of oxidative stress, which plays an important role in tumor proliferation, invasion, angiogenesis, and treatment. However, the relationship between mitochondrial oxidative stress-related genes and glioblastoma (GBM) remains unclear. This study aimed to...

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Share to Cancer, Hypoxia, and Metabolism
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PMID: 36814293
DOI: 10.1186/s12967-023-03970-6

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