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Trimethylamine N-oxide and risk of inflammatory bowel disease: A Mendelian randomization study

25 Aug 2023

Abstract excerpt

A previous study suggested that inflammatory bowel disease (IBD) patients have low plasma levels of trimethylamine N-oxide (TMAO). In the present study, we examined this hypothesis using Mendelian randomization analysis. We used summary statistics data for single-nucleotide polymorphisms associated with plasma levels of TMAO, and the corresponding data for IBD from a genome-wide association meta-analysis of...

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PMID: 37653747
DOI: 10.1097/md.0000000000034758

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