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Article

Unequal causality between autoimmune thyroiditis and inflammatory bowel disease: a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Bai Siyang, Yu Yunfeng, Yang Xinyu, Hu Gang, Wu Jingyi, Tong Keke, Yin Yuman, Deng Juan, Chen Cong, Tan Chuanchuan

Abstract excerpt

Objective: This study aims to analyze the causal relationship between autoimmune thyroiditis (AIT) and inflammatory bowel disease (IBD) using bidirectional Mendelian randomization (MR). Methods: Single nucleotide polymorphisms were obtained from FinnGen. Exposure-outcome causality was assessed using inverse variance weighted, MR-Egger, and weighted median. MR-Egger intercept, Cochran's Q, and leave-one-out...

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Causality
Colitis, Ulcerative
Crohn Disease
Inflammatory Bowel Diseases
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Thyroiditis, Autoimmune

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Identifiers

PMID: 39512756
DOI: 10.3389/fendo.2024.1387482
PMCID: PMC11540656

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