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Article

The association of alanine aminotransferase and diabetic microvascular complications: A Mendelian randomization study

19 Jan 2023

Abstract excerpt

Aims Alanine aminotransferase (ALT) is positively related to diabetes risk in observational studies, whereas Mendelian randomization supports a linear causal association. In contrast, the relationship between ALT and diabetic nephropathy, and diabetic retinopathy is counter-intuitive in observational studies. Furthermore, no MR study has examined their causal association. The study aimed to investigate whether...

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PMID: 36742400
DOI: 10.3389/fendo.2023.1104963

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