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Functional Mutations in the microRNA-155 Promoter Modulate its Transcription Efficiency and Expression.

Molecular biotechnology - 1 Sept 2024

Li Congcong, Zhao Wanxia, Zhou Huijie, Wu Jiao, Huo Yong, Jiang Dongfeng, Ji Xiangbo, Liu Kun, Xu Qiuliang, Li Wantao

Abstract excerpt

Limited research has been conducted on porcine miR-155 promoters, and previous study from our group have identified two haplotypes (TT and CC) in different pig breeds, each associated with five fully linked mutation sites within or near the miR-155 gene (Li et al. Dev Comp Immunol 39(1):110-116, 2013). In this study, the promoter region of porcine miR-155 was screened, and two important transcription factors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37624482
DOI: 10.1007/s12033-023-00857-1

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