Article
Identification of functional mutations at FOXP3 binding site within BIC gene that alter the expression of miR-155 in pigs.
Gene - 20 Jun 2020
Wang Daoyuan, Zhang Wei, Guo Jingying, Wu Yalan, Li Xinyun, Zhao Shuhong, Zhu Mengjin
Abstract excerpt
MiR-155 is an immune microRNA encoded within the BIC gene. Dozens of researches have uncovered the importance of high expression of miR-155 in promoting the development of immune organs and strengthening immune response and inflammatory response. Some natural mutations located in the miR-155/BIC region were revealed to disturb the expression level of miR-155 in several mammalian species, and our previous study...
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