Article
Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy
25 Aug 2023
Abstract excerpt
Systemic modalities are crucial in the management of disseminated malignancies and liquid tumours. However, patient responses and tolerability to treatment are generally poor and those that enter remission often return with refractory disease. Combination therapies provide a methodology to overcome chemoresistance mechanisms and address dose-limiting toxicities. A deeper understanding of tumorigenic processes at...
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