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Management of PALB2 ‐associated breast cancer: A literature review and case report

1 Aug 2023

Abstract excerpt

Key Clinical Message Germline pathogenic variants (PV) of thePALB2tumor suppressor gene are associated with an increased risk of breast, pancreatic, and ovarian cancer. In previous research,PALB2‐associated breast cancer showed aggressive clinicopathological phenotypes, particularly triple‐negative subtype, and higher mortality regardless of tumor stage, type of chemotherapy nor hormone receptor status. The...

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PMID: 37621724
DOI: 10.1002/ccr3.7747

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