Article
Near-neutrality, robustness, and epigenetics.
Genome biology and evolution - 1 Jan 2011
Ohta Tomoko
Abstract excerpt
The nearly neutral theory emphasizes the interaction of drift and weak selection in evolution. With progress of genome biology, the applicability of the nearly neutral theory has expanded. The genome-wide analyses of synonymous and nonsynonymous substitutions at protein-coding regions show prevalence of very weak selection. Many patterns of evolution of gene regulation are also in agreement with the nearly...
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