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Article

High expression of bone morphogenetic protein 1 (BMP1) is associated with a poor survival rate in human gastric cancer, a dataset approaches.

Genomics - 1 Jan 2021

Rafi Jahirul Hasnat, Jafar Tamanna, Pathan Mohammad Turhan, Reza Rumman, Islam Saiful, Sourna Israt Jahan, Alam Rahat, Samad Abdus, Ahammad Foysal

Abstract excerpt

Bone morphogenetic protein 1 (BMP1) is a secreted metalloprotease of the astacin M12A family of bone morphogenetic proteins (BMPs). BMP1 activates transforming growth factor-β (TGF-β) and BMP signaling pathways by proteolytic cleavage, which has dual roles in gastrointestinal tumor development and progression.TGF-β promotes invasion and metastasis of gastric cancer (GC) by the help of BMP1, so upregulation of the...

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PMID: 33189777
DOI: 10.1016/j.ygeno.2020.11.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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