Article
Clinical importance of the range of detectable variants between the Oncomine Dx target test and a conventional single-gene test for EGFR mutation.
Scientific reports - 23 Aug 2023
Sakaguchi Tadashi, Iketani Akemi, Esumi Seiya, Esumi Maki, Suzuki Yuta, Ito Kentaro, Fujiwara Kentaro, Nishii Yoichi, Katsuta Koji, Yasui Hiroki, Taguchi Osamu, Hataji Osamu
Abstract excerpt
Although we have experienced some cases with discordant results between the Oncomine Dx target test (ODxTT) and conventional single gene tests for detecting EGFR alterations, the clinical efficacy of EGFR-TKIs in these discordant cases remains little known. We retrospectively reviewed consecutive patients with non-small-cell lung cancer whose FFPE samples were simultaneously submitted for the ODxTT, and a PNA-LNA...
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