Article
Evaluation of appropriate conditions for Oncomine DxTT testing of FFPE specimens for driver gene alterations in non-small cell lung cancer.
Thoracic cancer - 1 Aug 2023
Iwama Eiji, Yamamoto Hidetaka, Okubo Fumihiko, Ijichi Kayo, Ibusuki Ritsu, Shiaraishi Yoshimasa, Yoneshima Yasuto, Tanaka Kentaro, Oda Yoshinao, Okamoto Isamu
Abstract excerpt
BACKGROUND: The Oncomine Dx Target Test Multi-CDx System (ODxTT) is a next-generation sequencing panel approved as a companion diagnostic for drugs targeted to corresponding gene alterations in non-small cell lung cancer. However, appropriate slide conditions for ODxTT have remained unclear. METHODS: We focused on the production of the number of tumor cells on a formalin-fixed paraffin-embedded (FFPE) section and...
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