Article
Comparison of the analytical performance between the Oncomine Dx Target Test and a conventional single gene test for epidermal growth factor receptor mutation in non-small cell lung cancer.
Thoracic cancer - 1 Feb 2021
Sakaguchi Tadashi, Iketani Akemi, Furuhashi Kazuki, Nakamura Yuki, Suzuki Yuta, Ito Kentaro, Fujiwara Kentaro, Nishii Yoichi, Katsuta Koji, Taguchi Osamu, Hataji Osamu
Abstract excerpt
BACKGROUND: Next-generation sequencing (NGS) has been implemented in clinical oncology to analyze multiple genes and to guide targeted therapy; however, little is known about the performance of the Oncomine Dx Target Test compared with conventional single gene tests for detecting EGFR mutations. The objective of this study was to evaluate the performance of the Oncomine Dx Target Test compared with a PNA-LNA PCR...
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