Article
Resistance Mechanisms and Clinical Features of Fluconazole-Nonsusceptible Candida tropicalis Isolates Compared with Fluconazole-Less-Susceptible Isolates.
Antimicrobial agents and chemotherapy - 1 Jun 2016
Choi Min Ji, Won Eun Jeong, Shin Jong Hee, Kim Soo Hyun, Lee Wee-Gyo, Kim Mi-Na, Lee Kyungwon, Shin Myung Geun, Suh Soon Pal, Ryang Dong Wook, Im Young Jun
Abstract excerpt
We investigated the azole resistance mechanisms and clinical features of fluconazole-nonsusceptible (FNS) isolates of Candida tropicalis recovered from Korean surveillance cultures in comparison with fluconazole-less-susceptible (FLS) isolates. Thirty-five clinical isolates of C. tropicalis, comprising 9 FNS (fluconazole MIC, 4 to 64 μg/ml), 12 FLS (MIC, 1 to 2 μg/ml), and 14 control (MIC, 0.125 to 0.5 μg/ml)...
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