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Article

Autoimmune hypothyroidism and endometriosis: evidence from bidirectional Mendelian randomization and an independent clinical cohort analysis.

Frontiers in endocrinology - 1 Jan 2026

Shi Jiawei, Jiang Weijie, Chen Hui, Zhou Liming, Hu Juwei

Abstract excerpt

Background: Observational studies have reported comorbidity between autoimmune thyroid disease and endometriosis, but whether this reflects a direct causal relationship or shared susceptibility remains unclear. We evaluated the bidirectional relationship between autoimmune hypothyroidism (AIHT) and endometriosis using Mendelian randomization (MR) and an independent clinical cohort. Methods: Genome-wide...

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Identifiers

PMID: 42621321
DOI: 10.3389/fendo.2026.1898299
PMCID: PMC13487738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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