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Article

Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.

Journal of cancer research and clinical oncology - 1 Nov 2023

Pham Thu Thi, Nimptsch Katharina, Papadimitriou Nikos, Aleksandrova Krasimira, Jenab Mazda, Gunter Marc J, Le Marchand Loic, Li Li, Lynch Brigid M, Castellví-Bel Sergi, Phipps Amanda I, Schmit Stephanie L, Brenner Hermann, Ogino Shuji, Giovannucci Edward, Pischon Tobias

Abstract excerpt

PURPOSE: Resistin, a novel pro-inflammatory protein implicated in inflammatory processes, has been suggested to play a role in colorectal development. However, evidence from observational studies has been inconsistent. Mendelian randomization may be a complementary method to examine this association. METHODS: We conducted a two-sample Mendelian randomization to estimate the association between genetically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37599317
DOI: 10.1007/s00432-023-05193-0
PMCID: PMC10602946

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