Article
Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2015
Thrift Aaron P, Gong Jian, Peters Ulrike, Chang-Claude Jenny, Rudolph Anja, Slattery Martha L, Chan Andrew T, Locke Adam E, Kahali Bratati, Justice Anne E, Pers Tune H, Gallinger Steven, Hayes Richard B, Baron John A, Caan Bette J, Ogino Shuji, Berndt Sonja I, Chanock Stephen J, Casey Graham, Haile Robert W, Du Mengmeng, Harrison Tabitha A, Thornquist Mark, Duggan David J, Le Marchand Loïc, Lindor Noralane M, Seminara Daniela, Song Mingyang, Wu Kana, Thibodeau Stephen N, Cotterchio Michelle, Win Aung Ko, Jenkins Mark A, Hopper John L, Ulrich Cornelia M, Potter John D, Newcomb Polly A, Hoffmeister Michael, Brenner Hermann, White Emily, Hsu Li, Campbell Peter T
Abstract excerpt
BACKGROUND: High body mass index (BMI) is consistently linked to increased risk of colorectal cancer for men, whereas the association is less clear for women. As risk estimates from observational studies may be biased and/or confounded, we conducted a Mendelian randomization study to estimate the causal association between BMI and colorectal cancer. METHODS: We used data from 10,226 colorectal cancer cases and...
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