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Article

Sex Differences in Prognostic Implications of CYP2C19 Genotype After Drug-Eluting Stent Implantation.

Journal of the American Heart Association - 5 May 2026

Kim Soo-Jin, Her Ae-Young, Joo Hyung Joon, Chang Kiyuk, Kim Byeong-Keuk, Song Young Bin, Ahn Sung Gyun, Suh Jung-Won, Lee Sang Yeup, Cho Jung Rae, Kim Hyo-Soo, Jeong Young-Hoon, Kim Moo Hyun, Lim Do-Sun, Shin Eun-Seok

Abstract excerpt

BACKGROUND: Dual-antiplatelet therapy is standard after percutaneous coronary intervention, but clopidogrel responsiveness varies with CYP2C19 loss-of-function alleles. Whether the genotype conveys different prognostic significance between sexes is uncertain. METHODS: We analyzed 4630 East-Asian patients with acute coronary syndrome in the PTRG-DES (Platelet Function- and Genotype-Related Long-Term Prognosis in...

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Share to Acute Coronary Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP2C19

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Source

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Identifiers

PMID: 42047190
DOI: 10.1161/JAHA.125.045981
PMCID: PMC13279255

Genes

CYP2C19
DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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