Article
Bacterial Magnetosome-Hitchhiked Quick-Frozen Neutrophils for Targeted Destruction of Pre-Metastatic Niche and Prevention of Tumor Metastasis.
Advanced healthcare materials - 1 Nov 2023
Han Xiaoqing, Wang Xingbo, Yan Jiao, Song Panpan, Wang Yanjing, Shang Chao, Wu Yunyun, Zhang Hua, Wang Zhenxin, Zhang Haiyuan, Li Xi
Abstract excerpt
Premetastatic niche (PMN) is a prerequisite for tumor metastasis. Destruction of PMN can significantly suppress the tumor metastasis. Bone marrow-derived cells are usually recruited into the premetastatic organs to support PMN formation, which can be orchestrated by tumor-derived secreted factors. Neutrophils can chemotactically migrate towards the inflammatory sites and consume tumor-derived secreted factors,...
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