Article
Mutation in yl-HOG1 represses the filament-to-yeast transition in the dimorphic yeast Yarrowia lipolytica.
Microbial cell factories - 16 Aug 2023
Rzechonek Dorota A, Szczepańczyk Mateusz, Mirończuk Aleksandra M
Abstract excerpt
BACKGROUND: Yarrowia lipolytica is a dimorphic fungus, which switches from yeast to filament form in response to environmental conditions. For industrial purposes it is important to lock cells in the yeast or filamentous form depending on the fermentation process. yl-Hog1 kinase is a key component of the HOG signaling pathway, responsible for activating the osmotic stress response. Additionally, deletion of...
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