Article

Integrative Analysis of Transcriptome-Wide Association Study and Gene-Based Association Analysis Identifies Candidate Genes Associated With Juvenile Idiopathic Arthritis

2022-05-31

Abstract excerpt

<h4>Background: </h4> The current genome-wide association study (GWAS) of Juvenile idiopathic arthritis (JIA) suffers from the low power due to limited sample size, as well as suffers from the interpretation issue due to most GWAS signals located in non-coding regions. Gene-level analysis is able to aggregate many SNPs with small effects to improve the association power, and further benefit the better understandin...

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Literature Corpus work: 2eb4ffb5-f592-5890-83ab-1022f3692de9
DOI: 10.21203/rs.3.rs-1690480/v1

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