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Article

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules

2 Feb 2021

Abstract excerpt

Inflammation is a host protection mechanism that eliminates invasive pathogens from the body. However, chronic inflammation, which occurs repeatedly and continuously over a long period, can directly damage tissues and cause various inflammatory and autoimmune diseases. Pattern recognition receptors (PRRs) respond to exogenous infectious agents called pathogen-associated molecular patterns and endogenous danger...

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PMID: 33603747
DOI: 10.3389/fimmu.2020.618231

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