Article
RAD51 and Infertility: A Review and Case-Control Study.
Biochemical genetics - 1 Apr 2024
Sahota Jatinder Singh, Thakur Ranveer Singh, Guleria Kamlesh, Sambyal Vasudha
Abstract excerpt
RAD51 is a highly conserved recombinase involved in the strand invasion/exchange of double-stranded DNA by homologous single-stranded DNA during homologous recombination repair. Although a majority of existing literature associates RAD51 with the pathogenesis of various types of cancer, recent reports indicate a role of RAD51 in maintenance of fertility. The present study reviews the role of RAD51 and its...
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