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Article

Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human

18 Jun 2019

Abstract excerpt

Spermatogenesis is a complicated process including spermatogonial stem cells (SSCs) self-renewal and differentiates into mature spermatozoa. MicroRNAs (miRNAs) as a class of small non-coding RNAs play a crucial role during the process of spermatogenesis. However, the function of a plenty of miRNAs on spermatogenesis and the potential mechanisms remain largely unknown. Here, we show that genetically conditional...

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PMID: 31275170
DOI: 10.3389/fphys.2019.00765

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