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Article

Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility.

Systems biology in reproductive medicine - 1 Dec 2017

Ghasemi Hadi, Khodadadi Iraj, Fattahi Amir, Moghimbeigi Abbas, Tavilani Heidar

Abstract excerpt

Sperm DNA damage is one of the associated factors of idiopathic male infertility and abnormal spermatogenesis. This study was conducted to assess possible association between risk of male infertility with X-ray repair cross complementing group 1 (XRCC1) Arg399Gln (G to A) and DNA ligase 4 (LIG4) Thr9Ile (C to T) gene polymorphisms which are involved in different DNA repair pathways. In this case-control study 191...

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Source

Identifiers

PMID: 28991497
DOI: 10.1080/19396368.2017.1374488

Genes

LIG4
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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