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Article

Artificial Neural Network Analysis of Determinants of Tacrolimus Pharmacokinetics in Liver Transplant Recipients.

The Annals of pharmacotherapy - 1 May 2024

Du Yue, Zhang Yundi, Yang Zhiyan, Li Yue, Wang Xinyu, Li Ziqiang, Ren Lei, Li Yan

Abstract excerpt

BACKGROUND: The efficacy and toxicity of tacrolimus are closely related to its trough blood concentrations. Identifying the influencing factors of pharmacokinetics of tacrolimus in the early postoperative period is conducive to the optimization of the individualized tacrolimus administration protocol and to help liver transplant (LT) recipients achieve the target blood concentrations. OBJECTIVE: This study aimed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37559252
DOI: 10.1177/10600280231190943

Genes

CYP3A5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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