Article
Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes.
Diabetes care - 1 Oct 2023
Ahmed Altayeb, Amin Hasnat, Drenos Fotios, Sattar Naveed, Yaghootkar Hanieh
Abstract excerpt
OBJECTIVE: To investigate the causal association of type 2 diabetes and its components with risk of vascular complications independent of shared risk factors obesity and hypertension and to identify the main driver of this risk. RESEARCH DESIGN AND METHODS: We conducted Mendelian randomization (MR) using independent genetic variants previously associated with type 2 diabetes, fasting glucose, HbA1c, fasting...
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