Article
Machine learning-based ensemble approach in prediction of lung cancer predisposition using XRCC1 gene polymorphism.
Journal of biomolecular structure & dynamics - 1 Sept 2024
Choudhary Abhishek, Anand Adarsh, Singh Amrita, Roy Pratima, Singh Navneet, Kumar Vinay, Sharma Siddharth, Baranwal Manoj
Abstract excerpt
The employment of machine learning approaches has shown promising results in predicting cancer. In the current study, polymorphisms data of five single nucleotide polymorphisms (SNPs) of DNA repair gene XRCC1 (XRCC1 399, XRCC1 194, XRCC1 206, XRCC1 632, XRCC1 280) of the north Indian population along with four smoking status data is considered as an input to the proposed ensemble model to predict the risk of...
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