Article
Association and multiple interaction analysis among five XRCC1 polymorphic variants in modulating lung cancer risk in North Indian population.
DNA repair - 1 Nov 2016
Singh Amrita, Singh Navneet, Behera Digambar, Sharma Siddharth
Abstract excerpt
XRCC1 is a scaffold protein that provides for interaction of DNA polymerase, DNA ligase and damaged DNA. Genotyping was done for the five non-synonymous and synonymous variants of XRCC1 i.e. XRCC1, Arg194Trp, Pro206Pro, Arg280His, Arg399Gln, Gln632Gln. Logistic regression analysis was used to analyze the association of XRCC1 with lung cancer, followed by data mining analysis which included both...
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