Article
Nodal Metastases Associated With Fusion Oncogenes Are Age Dependent in Young Adult Patients With Thyroid Cancer.
The Journal of clinical endocrinology and metabolism - 21 Dec 2023
Li Haorong, Han Rulai, Meng Lingyang, Sun Yingkai, Zhao Ming, Zhou Wei, Xie Jing, Yu Danyan, Shen Liyun, Zhou Yulin, Wang Shu, Yan Jiqi, Wang Weiqing, Ye Lei
Abstract excerpt
CONTEXT: Fusion oncogenes, especially those involving RET or NTRK, are known drivers of papillary thyroid cancer (PTC). They are prevalent in pediatric patients and correlate with aggressive tumor behavior. OBJECTIVE: We explored the age dependence of fusion oncogenes and aggressive tumor behavior in young adult PTC patients. EXPERIMENTAL DESIGN: We examined 150 tumors from 142 PTC patients aged between 17∼35...
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