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Article

NTRK fusion analysis reveals enrichment in Middle Eastern BRAF wild-type PTC

1 Feb 2021

Abstract excerpt

Objective: Fusions involving neurotrophic tyrosine receptor kinase (NTRK) are known oncogenic drivers in a broad range of tumor types. It recently gained attention as a predictor of targeted therapy since selective NTRK inhibitors are now approved in the US and Europe for patients with solid tumors harboring gene fusions. However, estimation of NTRK gene fusion/alteration frequency and its clinicopathological...

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PMID: 33524004
DOI: 10.1530/eje-20-1345

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