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Article

Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Apr 2022

Franco Aime T, Ricarte-Filho Julio C, Isaza Amber, Jones Zachary, Jain Neil, Mostoufi-Moab Sogol, Surrey Lea, Laetsch Theodore W, Li Marilyn M, DeHart Jessica Clague, Reichenberger Erin, Taylor Deanne, Kazahaya Ken, Adzick N Scott, Bauer Andrew J

Abstract excerpt

PURPOSE: In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary thyroid cancer samples reported by The Cancer Genome Atlas project suggested that reclassification of thyroid cancer into molecular subtypes, RAS-like and BRAF-like, better reflects clinical behavior than sole reliance on pathologic classification. The aim of this study was to categorize the common oncogenic variants in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35015563
DOI: 10.1200/JCO.21.01861
PMCID: PMC8966969

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