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Article

C-reactive protein gene polymorphisms (rs1205) in Asian Indian patients with Takayasu arteritis: Associations and phenotype correlations.

International journal of rheumatic diseases - 1 Mar 2018

Nair Aswin M, Goel Ruchika, Hindhumati Mohan, Shah Krati, Chandana Puneet, Jayaseelan Visalakshi, Jayakanthan Kabeerdoss, Joseph George, Danda Sumita, Danda Debashish

Abstract excerpt

BACKGROUND/PURPOSE: Normal C-reactive protein (CRP) in active Takayasu arteritis (TA) is a dilemma. We attempted to validate our pilot study finding of rs1205 in CRP gene being protective against TA. METHODS: Genomic DNA of 104 patients and 185 sex-matched healthy controls were genotyped for rs1205 by Taqman assay. Clinical details, demography, angiographic and activity scores (Indian Takayasu arteritis score...

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PMID: 29024426
DOI: 10.1111/1756-185X.13180

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CRP
MAF

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