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Bone Remodeling and Bone Structural Genes in Legg-Calvé-Perthes Disease: The OPG rs2073618 and IL-6 rs1800795 Are Associated with High Risk in Mexican Patients.

DNA and cell biology - 1 Jun 2024

Cruz-Ortíz Blanca Lucía, Hernández-Zamora Edgar, Reyes-Maldonado Elba, Rodríguez-Olivas Armando Odiseo, Rubio-Lightbourn Julieta, Martínez-Ramírez Celeste O, Castro-Hernández Clementina, Lezama-Palacios Ruth, Casas-Avila Leonora

Abstract excerpt

Legg-Calve-Perthes disease (LCPD) is an idiopathic avascular necrosis of the pediatric femoral head. Bone remodeling and bone structural genes have the potential to contribute to the progression of LCPD when there is disequilibrium between bone resorption and bone formation. A case-control study was performed to search for associations of several common polymorphisms in the genes Receptor Activator for Nuclear...

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PMID: 38648538
DOI: 10.1089/dna.2023.0411

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Bone Remodeling and Bone Structural Genes in Legg-Calvé-Perthes Disease: The OPG rs2073618 and IL-6 rs1800795 Are Associated with High Risk in Mexican Patients.PMID 38648538Read ↗

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