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Article

Identifying genetic loci that are associated with changes in gene expression in PTSD in a South African cohort.

Journal of neurochemistry - 1 Aug 2023

Swart Patricia C, Du Plessis Morne, Rust Carlien, Womersley Jacqueline S, van den Heuvel Leigh L, Seedat Soraya, Hemmings Sian M J

Abstract excerpt

The molecular mechanisms underlying posttraumatic stress disorder (PTSD) are yet to be fully elucidated, especially in underrepresented population groups. Expression quantitative trait loci (eQTLs) are DNA sequence variants that influence gene expression, in a local (cis-) or distal (trans-) manner, and subsequently impact cellular, tissue, and system physiology. This study aims to identify genetic loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37522158
DOI: 10.1111/jnc.15919
PMCID: PMC10953375

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