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Article

Lipocalin-2 promotes adipose–macrophage interactions to shape peripheral and central inflammatory responses in experimental autoimmune encephalomyelitis

28 Jul 2023

Abstract excerpt

OBJECTIVE: Accumulating evidence suggests that dysfunctional adipose tissue (AT) plays a major role in the risk of developing multiple sclerosis (MS), the most common immune-mediated and demyelinating disease of the central nervous system. However, the contribution of adipose tissue to the etiology and progression of MS is still obscure. This study aimed at deciphering the responses of AT in experimental...

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PMID: 37517520
DOI: 10.1016/j.molmet.2023.101783

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